Considering a move from TX to SC

So I'm interviewing this Friday for a job that I legitimately want. It would be incredible for my career. It's in Columbia, SC. (Not trying to count my chickens but I still want some advice)

I've wanted to get out of Texas for 2 major reasons.

  1. The specific type of tree that im horrifically allergic to only grows in Texas, Oklahoma and New Mexico and it's effected my health pretty bad. And I live in DFW which is pollution central along with over population (8 million now). So I need to leave for that.

  2. Political reasons, which I won't go into detail about as it seems fairly obvious.

I guess my question is...

Would I just being out of the fryer and into the frying pan kind of situation? My wife is also a public school teacher and I saw some things that make SC more agreeable for her as well. (TX teacher benefits are HORRIFIC).

I'm just looking for some advice and or insight on others.